June 9, 2025

Making Your Own Penicillin at Home - It's A Process - Perhaps Consider Oxymel, A Natural Antibiotic, Anti-Inflammatory Instead

By S.E. Gunn, PhD -�All News Pipeline

Since this article is about medicine, I shall begin with the usual�disclaimer:

The information provided in this article is for educational and informational purposes only and solely as a self-help tool for your own use. I am not, nor am I holding myself out to be a doctor/physician, nurse, physician's assistant, advanced practice nurse, or any other medical professional ("Medical Provider"), psychiatrist, psychologist, therapist, counselor, or social worker ("Mental Health Provider"), registered dietician or licensed nutritionist, or member of the clergy. I am not providing health care, medical or nutritional therapy services, or attempting to diagnose, treat, prevent, or cure any physical, mental, or emotional issue, disease, or condition. The information provided in this article pertaining to parasites is not intended to be a substitute for the professional medical advice, diagnosis, or treatment provided by your own Medical Provider or Mental Health Provider. Always seek the advice of your own Medical Provider and/or Mental Health Provider regarding any questions or concerns you have prior to implementing any recommendations or suggestions from this article. Do not disregard medical advice or delay seeking medical advice because of information you have read in this article. Do not stop or start taking any medications without consulting your Medical Provider or Mental Health Provider. The information contained in this article has not been evaluated by the Food and Drug Administration. This article is for educational and informational purposes only, does not constitute medical advice, and does not establish any kind of patient-client relationship by your access of this article. Although I strive to provide accurate information, the information presented here is not a substitute for any kind of professional advice. Always consult a professional in the area for your particular needs and circumstances prior to making any professional, legal, medical, financial, or tax-related decisions.

. . . whether fungi associated with food production are potential penicillin producers or not.

They found:

Among different fungal species belonging to the genus Penicillium that are currently used as starter cultures in the food industry or that are frequently isolated from cured meat products, only one�was found to produce penicillin and possess the three penicillin biosynthetic genes. It is important that the commonly used cheese starters P. camemberti and P. roqueforti neither are penicillin producers nor possess the penicillin biosynthetic genes, which implies that they do not represent a risk regarding the problem of the presence of penicillin in food. . . .�P. griseofulvum�is frequently isolated from corn, wheat, barley, flour, and walnuts and from meat products, thus being a potential source for the presence of penicillin in food.

In other words, these researchers say you are being exposed to penicillin in your food by eating corn, wheat, barley, flour, walnuts, and meat products. The research was funded by the city of Leon, Spain and the�Spanish Agency for International Development Cooperation.�

Allergy Notice

Susan Morrow, in her text�A Step-by-Step Guide to Making Your Own Penicillin at Home, warns that about 10% of the population is either allergic or sensitive to penicillin. Allergy signs are hives and swollen eyes, tongue, or face. An anaphylactic reaction, while rare, includes shortness of breath and wheezing and normally happens within 1 hour of ingestion. Delayed reactions up to 8-10 days after ingesting penicillin would include a rash, nausea, vomiting, diarrhea, or indigestion.

Contra-Indicators

Susan Morrow also explains that if you have a blood clotting disorder (hemophilia) or asthma, you need to be cautious about taking penicillin. She also notes that a small amount of penicillin will pass to the fetus if taken during pregnancy.

History

Wikipedia tells us penicillin was discovered by Scottish physician Alexander Fleming in 1928. But that there is evidence that ancient cultures knew about using fungi and plants to treat infection. In 1941, the first test subject, a woman with cancer, received an injection of penicillin solution with no side effects. In 1941 Squibb, Merck, Pfizer, and Lederle became involved in the projection of penicillin. In 1943 antitrust laws were suspended for the production of penicillin. By mid-1943, penicillin was being mass produced. Antibiotic resistance was first reported in 1940 and continues to be a concern in Public Health.

Making Penicillin

The Thought Emporium provides a detailed video on how penicillin is made. You can see how complicated the process is. Antibiotics must be "grown" they can not be synthesized chemically.

But, you might point out, back in 1928 when penicillin was discovered, they didn't have all the wonderful equipment and processes we have today. I would counter with "but so many people died anyway, some of them from the other fungi in the 'penicillin solution' they were given. As more ways were found to isolate the penicillin fungi, fewer people died. That said, they HAVE been making penicillin from mold for thousands of years, well before the process we have today, so there must be a way to make it at home. And there are a few ways. The simplest way is offered by James Hershey Jr.:

1. Put bread in a bag or container (to keep it dry) and allow it to grow.
2. Once mold starts forming, take the bread out and crumble it into tiny pieces, then spritz it with a small amount of water (a very light mist)
3. Put back in container/bag and monitor
4. The mold will turn from white to blue to green.
5. When the majority of mold is green, it's time to harvest.

To use (it will taste bad and cause diarrhea & upset stomach):

1. Take a large cup
2. Add bread clumps with green mold
3. Add warm (NOT HOT) water
4. Mix well, then drink it.
5. Do this once a day - multiple times a day for acute needs

Hershey notes that you are� growing "other stuff" that MIGHT not be good for you, since with this method, you do not attempt to separate the "penicillin" from the other fungi growing on the bread.�

1. Take time to remove only the green mold from the bread
2. Take the separated mold and place directly on the cleaned wound & wrap with gauze, pads, or�
3. Repeat often (depending on wound healing rate)

Then, he wipes this method right off the map by saying "just put raw honey on the wound". Honey is a natural antibiotic, will last thousands of years, and has been used as an antibiotic for millennia.

There are others who have instructions for making penicillin, requiring many steps and extra supplies:

Preppers Are We goes into much greater detail for making penicillin at home:

1. Isolating Penicillin Bacteria

2. Making a Host Culture for the Penicillin to Grow On using boiled potatoes

�Natural penicillin� derived directly from mold is very sensitive to stomach acid. If you drink it as a tea, it will be destroyed before it makes it to your bloodstream. The only way to make this penicillin work is it to inject it and that is not good at this stage because of the impurity and is not recommended!. To get the benefits of penicillin from mold, it has to be further cultured.

3. Streaking Your �Petri Dish� - the process of moving your penicillin spores to enable it to reproduce.

4. Let Your Penicillin Grow -� for about a week, keep it covered

5. Fermenting Your Penicillin - for about a week

6. Extracting the Penicillin

In theory, you could use this extracted penicillin now. However, the penicillin is very unstable. You�d have to use it right away. Considering that most infections need multiple rounds of antibiotics to treat, your whole efforts would be for nothing. Thus, you have to do the fairly complicated and scientific step of further extracting the penicillin.

7. Further Extraction -�

Ethyl acetate is used to completely extract pure penicillin. The penicillin dissolves into the ethyl acetate. Then the ethyl can be evaporated, leaving you with pure penicillin.

1. Allow bread to grow mold on it
2. Add solution, allow to incubate for 7 days
3. Extract the penicillin

In Greek Prepper's article�How to Make Penicillin At Home: The Complete Guide�they also provide 3 steps:

1. Grow
2. Prepare to purify
3. Purify

Greek Prepper also provides a "simpler method":

1. Grow from bread
2. Prepare the solution
3. Separate the penicillin using the solution
4. Extract the penicillin

Susan Morrow in her text A Step-by-Step Guide to Making Your Own Penicillin at Home�provides the following 9 steps:

1. Grow the mold and incubate the fungus
2. Preparing the medium for growth
3. Inoculate the medium
4. Extract the penicillin
5. Carbon treatment
6. Crystallization
7. Washing the crystals
8. Drying the crystals
9. Preparing your penicillin

Supplies recommended to make your own penicillin

• Spritz Bottle
• Food Grade Corn Steep Liquor
• Lactose
• Calcium Carbonate
• Phenylacetamide
• Hydrochloric Acid or Phosphoric Acid
• Ethyl Acetate (Solvent)
• Activated Charcoal
• Potassium Carbonate Food Grade or Potassium Bicarbonate Food Grade
• Butanol Food Grade or Propanol
• Heat Resistant Flask with Bung
• Food Scale
• pH Test Kit
• Fine Mesh Cloth or Filter Paper
• Separation Funnel with Stand

So, . . . How about an Oxymel instead?

At this point, I am sure you are feeling overwhelmed at what it would take to actually create penicillin at home, perhaps you might consider the following natural antibiotic/anti-inflammatory oxymel from Speir Outdoors instead:

Supplies:

• Plastic or glass container with plastic lid
• Measuring cup with ounces
• Measuring spoons for 1/2 & 1 tbs
• Spatula�

Ingredients:

• 7 oz raw, unfiltered honey (local is best)
• 4 oz raw, unfiltered apple cider vinegar with mother
• 2 tbs ground turmeric (fresh is best) does stain
• 1/2 tbs ground black pepper (or cayenne pepper if you like heat)

Directions:

• Combine all ingredients in plastic or glass jar
• Put plastic lid on and shake it well

To use as a pain reliever:

• 1 tbs twice a day for pain

To use as an antibiotic:

• On first day take 1tbs per hour
• On second day take 1 tbs every 2 hours
• On third day take 1 tbs every 3 hours
• Starting day 4, take 1 tbs twice a day

This oxymel can be used as both a preventative and a curative.�

[RELATED:�Make Your Own Medicine from God's Gifts! Teas, Infusions, Decoctions, Sun Brews, Syrups, Elixirs, Oxymels, Infusions, Salves, Ointments, Tinctures, Poultices, Compresses, & Washes]

[RELATED:�What Ails You? It Could Be Parasites. How Would You Know and How Do You Get Rid of Them?]

On the other hand, if you give making penicillin at home a try, please let us know which method you used and what your results were in the comments below.